The Duodopa Gel therapy can be used by people with Parkinson's disease when their many doses of oral levodopa taken during the day fail to keep them in their best state of mobility for enough of the waking day or provide a good quality of life.
It is basically a continuous infusion of the standard Parkinson’s medication of Levodopa and Carbidopa into the intestine where it can be absorbed without the delay of erratic stomach emptying.
It allows a constant amount of Levodopa to be present in the blood, which can reduce motor fluctuations and so decrease the number of times people alternate between significant "off" time and uncontrolled movement (dyskinesia).
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